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Modern Production of Vaccines

Спеціальність: Biotechnology and Bioengineering
Код дисципліни: 8.162.00.M.26
Кількість кредитів: 3
Кафедра: Technology of Biologically Active Substances, Pharmacy and Biotechnology
Лектор: Associate Professor Komarovska-Porokhnyavets Olena Zoryanivna
Семестр: 4 семестр
Форма навчання: денна
Результати навчання:
• knowledge of classification and characteristics of vaccine preparations; of the composition of the vaccines; of basics of vaccinal prevention and mechanisms of antibody production and the basics of the immune response of the vaccinated organism, contraindications to vaccination;
• understanding of the technological processes for the production of vaccines and methods of quality control that guarantee effective immunological products of acceptable quality;
• ability to analyze and generalize the received knowledge of the technology of vaccines and to build the technological scheme of industrial production of vaccines.
Необхідні обов'язкові попередні та супутні навчальні дисципліни:
Prerequisites:
• Genetics (general and molecular);
• Biotechnology of immunopreparations and probiotics;
• Bioengineering (cell and genetic).
Co-requisites:
• Molecular Biotechnology and Bioengineering;
• Immunoglobulin and DNA diagnostics and identification of GMOs
Biotechnology and bioengineering of plants and genome analysis methods
Короткий зміст навчальної програми:
Basic biotechnology concept of vaccinology. Vaccines. Classification of vaccines. The composition of the vaccines. Anatoxins. Adjuvants: a classification according to origin, physical and chemical properties and characteristics. Bacterial vaccines for prevention of infectious diseases. Technological scheme of production of bacterial vaccines. Viral vaccines for the prevention of infectious diseases. The composition and technology of production of combined vaccines. Peptide and ribosomal vaccines. Scheme of production of ribosomal vaccines. Plant-based vaccines. Industrial production of vaccines. Requirements for vaccines. Quality control of vaccines. Parameters of quality of vaccines.
Рекомендована література:
1. Ада Г., Рамсей А. Вакцины, вакцинация и иммунный ответ: Пер. С англ. - М.:Медицина, 2002. - 344 с.
2. Биотехнология / под ред. Е.С.Воронова. - С-Пб.: Гиорд, 2008. - 703 с.
3. Биотехнология. Принципы и применение. / Под ред. Хиггинса И., Беста Д., Джонса Дж. - М.: Мир, 1988. - 480 с.
Методи і критерії оцінювання:
• current control: oral examination, individual written tests (40%)
• summary control: examination (exam) written-oral form (60%)