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Medical Biotechnology

Major: Pharmacy
Code of Subject: 7.226.00.M.18
Credits: 5
Department: Technology of Biologically Active Substances, Pharmacy and Biotechnology
Lecturer: Associate Professor Hubrii Zoriana
Semester: 2 семестр
Mode of Study: денна
Learning outcomes:
• The ability to apply methods of biosynthesis;
• The ability to apply a holistic view of formed biosynthesis in search of new drug substances;
• The ability to develop processes and methods of new drug substances and products;
• The ability to detect a correspondence between the structure of matter, its physical and chemical properties, reactivity and methods of synthesis;
• The ability to compare, choose alternative ways of obtaining medicines, apply knowledge of the microbiological processes to produce pharmaceutical substances, design new biotechnological production of pharmaceuticals.
Required prior and related subjects:
Prerequisites: Organic Chemistry; Biological Chemistry and Molecular Biology; Microbiology;
Pharmaceutical Chemistry; Chemistry and Technology of Drug Substances
Co-requisites: Industries Technology of Pharmaceutical Production; Quality Control of Medicines;
Modeling and Design of Chemical-Pharmaceutical Companies in GMP system
Summary of the subject:
Getting of biodrugs. Bases of Immunobiotechnology and Immunochemistry, especially of biotechnological processes to produce antibiotics, amino acids and vitamins that are used as medicines or veterinary medicines. Technologies for producing vaccines and serums. The problems of isolation and purification of biologics. Microbial transformation of organic compounds to produce biologically active substances - substances of medicines.
Recommended Books:
1. Кантере В.М. Теоретические основы технологии микробиологических производств / Кантере В.М. - М.:Агропромиздат, 1990. – 272с.
2. Егоров Н.С. Основы учения об антибиотиках / Егоров Н.С. - М.:Наука, 2004.- 525 с.
3. Посохова К.А., Вікторов О.П. Антибіотики / Посохова К.А., Вікторов О.П. – Т.:Укрмедкнига, 2005. - 296с.
4. Л.М.Буценко. Технології мікробного синтезу лікарських засобів / Л.М.Буценко, Ю.М. Пенчук, Т.П.Пирог. - К.:НУХТ, 2010. – 323с.
Assessment methods and criteria:
• written reports from workshops, oral interviews, control work (30 points);
• final evaluation - 70points (control measure, test): written-oral form